![]() The reduction of the size of an organ or a tissue due to a decrease in the size and number of cells is defined as atrophy. The development of muscles in bodybuilders happens as a result of this physiological hypertrophy. When the organ is hypertrophied as a result of an increase in the functional demand or due to the stimulation coming from growth factors or hormones, this is called a physiological hypertrophy. ![]() Cells that are capable of division achieve this via both hyperplasia and hypertrophy but cells that are indivisible increase their tissue mass through hypertrophy. ![]() When the physiological or the pathological stress on an organ increases, the organ responds to it by trying to enhance the efficiency of its functions through an increase in its functional tissue mass. There is no change in the number of cells. Side by Side Comparison – Hypertrophy vs Atrophy in Tabular FormĪn increase in the size of the cells that results in an increase in the size of the affected organ is defined as hypertrophy. Similarities Between Hypertrophy and Atrophyĥ. This is the key difference between hypertrophy and atrophy. In hypertrophy, the number of cells of the affected organ remains the same despite the increase in its size however, in atrophy, the reduction of the size of the organ is accompanied by a decrease in the number of functional cells. An increase in the size of the cells that results in an increase in the size of the affected organ is defined as hypertrophy whereas the reduction of the size of an organ or a tissue due to a decrease in the size and number of cells is defined as atrophy. Hypertrophy and atrophy are two of the most common cellular changes seen in both physiological and pathological conditions.
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